Age and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipients. [electronic resource]
- The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Dec 2011
- 1352-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1557-3117
10.1016/j.healun.2011.08.001 doi
ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily B, Member 1--genetics Aging--immunology Child Cytochrome P-450 CYP3A--genetics Dose-Response Relationship, Drug Female Genotype Glomerular Filtration Rate--physiology Graft Rejection--immunology Heart Transplantation--immunology Humans Immunosuppressive Agents--pharmacokinetics Kidney--physiology Male Retrospective Studies Severity of Illness Index Tacrolimus--pharmacokinetics Time Factors Treatment Outcome