O'Neill, David J <br/><br/>
Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152).  [electronic resource] 

 -  Journal of medicinal chemistry  Oct 2011 
 - 6824-31 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm200733r  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acute Pain--drug therapy<br/>Administration, Oral<br/>Analgesics--chemical synthesis<br/>Animals<br/>Benzothiazoles--chemical synthesis<br/>Biological Availability<br/>Cell Line<br/>Chronic Pain--drug therapy<br/>Cricetinae<br/>Cyclic S-Oxides--chemical synthesis<br/>Dogs<br/>Humans<br/>Inflammation--drug therapy<br/>Injections, Intravenous<br/>Male<br/>Morpholines--chemical synthesis<br/>Neuralgia--drug therapy<br/>Norepinephrine Plasma Membrane Transport Proteins--antagonists & inhibitors<br/>Rats<br/>Stereoisomerism<br/>Thiadiazoles--chemical synthesis