TY - GEN AU - Sohn,Hae Won AU - Krueger,Peter D AU - Davis,Randall S AU - Pierce,Susan K TI - FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling SN - 1528-0020 PY - 2012///0214 KW - B-Lymphocytes KW - cytology KW - Cell Line KW - Down-Regulation KW - Humans KW - Immunological Synapses KW - metabolism KW - Intracellular Signaling Peptides and Proteins KW - Isoenzymes KW - Lymphocyte Activation KW - Mutant Proteins KW - chemistry KW - Phospholipase C gamma KW - Phosphorylation KW - Protein Processing, Post-Translational KW - Protein Transport KW - Protein Tyrosine Phosphatase, Non-Receptor Type 11 KW - Protein Tyrosine Phosphatase, Non-Receptor Type 6 KW - Protein-Tyrosine Kinases KW - Proto-Oncogene Proteins c-bcr KW - Proto-Oncogene Proteins c-vav KW - Receptors, Fc KW - Recombinant Fusion Proteins KW - Signal Transduction KW - Syk Kinase KW - Toll-Like Receptor 9 KW - antagonists & inhibitors KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural UR - https://doi.org/10.1182/blood-2011-05-353102 ER -