TY - GEN AU - Esterházy,Daria AU - Stützer,Ina AU - Wang,Haiyan AU - Rechsteiner,Markus P AU - Beauchamp,Jeremy AU - Döbeli,Heinz AU - Hilpert,Hans AU - Matile,Hugues AU - Prummer,Michael AU - Schmidt,Alexander AU - Lieske,Nora AU - Boehm,Bernhard AU - Marselli,Lorella AU - Bosco,Domenico AU - Kerr-Conte,Julie AU - Aebersold,Ruedi AU - Spinas,Giatgen Andreia AU - Moch,Holger AU - Migliorini,Cristiano AU - Stoffel,Markus TI - Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass SN - 1932-7420 PY - 2012///0120 KW - Adolescent KW - Amino Acid Sequence KW - Amyloid Precursor Protein Secretases KW - antagonists & inhibitors KW - Animals KW - Aspartic Acid Endopeptidases KW - Blood Glucose KW - analysis KW - Cells, Cultured KW - Diabetes Mellitus, Type 2 KW - drug therapy KW - Enzyme Inhibitors KW - pharmacology KW - Female KW - Gene Silencing KW - drug effects KW - Humans KW - Insulin KW - metabolism KW - Insulin Resistance KW - Insulin-Secreting Cells KW - cytology KW - Membrane Glycoproteins KW - Mice KW - Mice, Inbred C57BL KW - Middle Aged KW - Molecular Sequence Data KW - Plasmids KW - RNA, Small Interfering KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - genetics KW - Species Specificity KW - Substrate Specificity KW - Transfection N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cmet.2011.06.018 ER -