TY - GEN AU - Nixon,Mark AU - Upreti,Rita AU - Andrew,Ruth TI - 5α-Reduced glucocorticoids: a story of natural selection SN - 1479-6805 PY - 2012///0224 KW - 3-Oxo-5-alpha-Steroid 4-Dehydrogenase KW - chemistry KW - 5-alpha Reductase Inhibitors KW - Animals KW - Anti-Inflammatory Agents KW - Biomarkers KW - metabolism KW - Corticosterone KW - analogs & derivatives KW - Glucocorticoids KW - Humans KW - Hydrocortisone KW - Inflammation KW - drug therapy KW - Isoenzymes KW - Liver KW - drug effects KW - Receptors, Glucocorticoid KW - agonists KW - Selection, Genetic KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review UR - https://doi.org/10.1530/JOE-11-0318 ER -