Yoo, Byong Hoon

Oncogenic ras-induced down-regulation of pro-apoptotic protease caspase-2 is required for malignant transformation of intestinal epithelial cells. [electronic resource] - The Journal of biological chemistry Nov 2011 - 38894-903 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M111.290692 doi


Animals
Anoikis--genetics
Caspase 2--biosynthesis
Cell Line, Tumor
Cell Transformation, Neoplastic--genetics
Cysteine Endopeptidases--biosynthesis
Cytochromes c--genetics
Cytoplasm--genetics
Down-Regulation
Epithelial Cells--metabolism
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Neoplastic
High-Temperature Requirement A Serine Peptidase 2
Humans
Intestinal Mucosa--metabolism
MAP Kinase Kinase Kinases--genetics
Mice
Mitochondrial Proteins--genetics
Neoplasm Proteins--genetics
Rats
Serine Endopeptidases--genetics
Signal Transduction--genetics
ras Proteins--genetics