Inhibition of the p38 and PKA signaling pathways is associated with the anti-melanogenic activity of Qian-wang-hong-bai-san, a Chinese herbal formula, in B16 cells. [electronic resource]
- Journal of ethnopharmacology Jun 2012
- 622-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1872-7573
10.1016/j.jep.2011.08.043 doi
Animals Bleaching Agents--pharmacology Blotting, Western Cell Line, Tumor Cyclic AMP Response Element-Binding Protein--metabolism Cyclic AMP-Dependent Protein Kinases--antagonists & inhibitors Dose-Response Relationship, Drug Drugs, Chinese Herbal--pharmacology Intramolecular Oxidoreductases--metabolism Medicine, Chinese Traditional Melanins--biosynthesis Melanoma, Experimental--enzymology Mice Monophenol Monooxygenase--antagonists & inhibitors Oxidoreductases--metabolism Phosphorylation Plants, Medicinal Protein Kinase Inhibitors--pharmacology Signal Transduction--drug effects Skin Pigmentation--drug effects Spectrophotometry Time Factors p38 Mitogen-Activated Protein Kinases--antagonists & inhibitors