Reuland, Steven N <br/><br/>
The combination of BH3-mimetic ABT-737 with the alkylating agent temozolomide induces strong synergistic killing of melanoma cells independent of p53.  [electronic resource] 

 -  PloS one  2011 
 - e24294 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0024294  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alkylating Agents--pharmacology<br/>Animals<br/>Apoptosis--drug effects<br/>Biomimetic Materials--pharmacology<br/>Biphenyl Compounds--pharmacology<br/>Cell Line, Tumor<br/>Dacarbazine--analogs & derivatives<br/>Drug Synergism<br/>Female<br/>Gene Expression Regulation, Neoplastic--drug effects<br/>Humans<br/>Melanoma--pathology<br/>Mice<br/>Nitrophenols--pharmacology<br/>Piperazines--pharmacology<br/>Protein Structure, Tertiary<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>Sulfonamides--pharmacology<br/>Temozolomide<br/>Time Factors<br/>Tumor Suppressor Protein p53--metabolism<br/>Xenograft Model Antitumor Assays