TY - GEN AU - Slade,Dea AU - Dunstan,Mark S AU - Barkauskaite,Eva AU - Weston,Ria AU - Lafite,Pierre AU - Dixon,Neil AU - Ahel,Marijan AU - Leys,David AU - Ahel,Ivan TI - The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase SN - 1476-4687 PY - 2011///1115 KW - Actinomycetales KW - enzymology KW - Adenosine Diphosphate KW - analogs & derivatives KW - Adenosine Diphosphate Ribose KW - chemistry KW - Amino Acid Sequence KW - Biocatalysis KW - Catalytic Domain KW - Crystallography, X-Ray KW - Evolution, Molecular KW - Glycoside Hydrolases KW - antagonists & inhibitors KW - Humans KW - Hydrolysis KW - Models, Molecular KW - Molecular Sequence Data KW - Phylogeny KW - Poly (ADP-Ribose) Polymerase-1 KW - Poly Adenosine Diphosphate Ribose KW - Poly(ADP-ribose) Polymerases KW - genetics KW - Protein Conformation KW - Proteins KW - metabolism KW - Pyrrolidines KW - pharmacology N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/nature10404 ER -