Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function. [electronic resource]
- The Journal of neuroscience : the official journal of the Society for Neuroscience Aug 2011
- 12554-65 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1529-2401
10.1523/JNEUROSCI.3143-11.2011 doi
Analysis of Variance Animals Animals, Newborn Avoidance Learning--drug effects Cerebral Cortex--cytology Disks Large Homolog 4 Protein Electric Stimulation--methods Excitatory Amino Acid Antagonists--pharmacology Excitatory Postsynaptic Potentials--genetics Green Fluorescent Proteins--genetics Guanine Nucleotide Exchange Factors--deficiency Guanylate Kinases--metabolism Immunoprecipitation--methods In Vitro Techniques Locomotion--drug effects Membrane Proteins--metabolism Mice Mice, Inbred C57BL Mice, Knockout Neuroglia--drug effects Patch-Clamp Techniques--methods Phenols--pharmacology Piperidines--pharmacology Protein Binding--genetics Pyramidal Cells--physiology Receptors, N-Methyl-D-Aspartate--metabolism Synapses--physiology Synaptosomes--drug effects Transfection--methods