TY  - GEN
AU  - Bharadwaj,Uddalak
AU  - Marin-Muller,Christian
AU  - Li,Min
AU  - Chen,Changyi
AU  - Yao,Qizhi
TI  - Mesothelin confers pancreatic cancer cell resistance to TNF-α-induced apoptosis through Akt/PI3K/NF-κB activation and IL-6/Mcl-1 overexpression
SN  - 1476-4598
PY  - 2012///0203
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Apoptosis Regulatory Proteins
KW  - genetics
KW  - Caspase 3
KW  - metabolism
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Chromones
KW  - Coumarins
KW  - Cyclin A
KW  - Drug Resistance, Neoplasm
KW  - Enzyme Activation
KW  - GPI-Linked Proteins
KW  - Gene Expression
KW  - Gene Knockdown Techniques
KW  - Genes, Reporter
KW  - Humans
KW  - I-kappa B Kinase
KW  - antagonists & inhibitors
KW  - Interleukin-6
KW  - Luciferases, Renilla
KW  - biosynthesis
KW  - Mesothelin
KW  - Morpholines
KW  - Myeloid Cell Leukemia Sequence 1 Protein
KW  - NF-kappa B
KW  - Pancreatic Neoplasms
KW  - Phosphatidylinositol 3-Kinases
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Protein Transport
KW  - Proto-Oncogene Proteins c-akt
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - RNA Interference
KW  - Recombinant Proteins
KW  - S Phase
KW  - Tumor Necrosis Factor-alpha
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1186/1476-4598-10-106
ER  -