TY  - GEN
AU  - Jayaraman,Ramesh
AU  - Pilla Reddy,Venkatesh
AU  - Pasha,Mohammed Khalid
AU  - Wang,Haishan
AU  - Sangthongpitag,Kanda
AU  - Yeo,Pauline
AU  - Hu,Chang Yong
AU  - Wu,Xiaofeng
AU  - Xin,Liu
AU  - Goh,Evelyn
AU  - New,Lee Sun
AU  - Ethirajulu,Kantharaj
TI  - Preclinical metabolism and disposition of SB939 (Pracinostat), an orally active histone deacetylase inhibitor, and prediction of human pharmacokinetics
SN  - 1521-009X
PY  - 2012///0409
KW  - Administration, Oral
KW  - Animals
KW  - Benzimidazoles
KW  - administration & dosage
KW  - Biological Availability
KW  - Caco-2 Cells
KW  - Chromatography, Liquid
KW  - Cytochrome P-450 Enzyme System
KW  - metabolism
KW  - Dogs
KW  - Female
KW  - Histone Deacetylase Inhibitors
KW  - Humans
KW  - Male
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Microsomes, Liver
KW  - enzymology
KW  - Rats
KW  - Rats, Wistar
KW  - Tandem Mass Spectrometry
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1124/dmd.111.041558
ER  -