TY - GEN AU - Dowty,Martin E AU - Hu,George AU - Hua,Fengmei AU - Shilliday,F Barclay AU - Dowty,Heather V TI - Drug design structural alert: formation of trifluoroacetaldehyde through N-dealkylation is linked to testicular lesions in rat SN - 1092-874X PY - 2012///0213 KW - Acetaldehyde KW - analogs & derivatives KW - Animals KW - Cytochrome P-450 Enzyme System KW - metabolism KW - Dealkylation KW - drug effects KW - Dose-Response Relationship, Drug KW - Drug Design KW - Epididymis KW - Male KW - Microsomes, Liver KW - Rats KW - Rats, Sprague-Dawley KW - Testis N1 - Publication Type: Journal Article UR - https://doi.org/10.1177/1091581811413833 ER -