The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf⁺/⁻ heterozygous null mice. [electronic resource]
- Neuropharmacology Jan 2012
- 391-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1873-7064
10.1016/j.neuropharm.2011.08.015 doi
Analysis of Variance Animals Antidepressive Agents--therapeutic use Brain-Derived Neurotrophic Factor--deficiency Depression--drug therapy Disease Models, Animal Dose-Response Relationship, Drug Exploratory Behavior--drug effects Hippocampus--drug effects Imipramine--pharmacology Ketamine--pharmacology Male Mice Mice, Inbred C57BL Mice, Knockout Reaction Time--drug effects Receptor, trkA--metabolism Sulfonamides--pharmacology Swimming--psychology