Sphingosine-1-phosphate rapidly increases cortisol biosynthesis and the expression of genes involved in cholesterol uptake and transport in H295R adrenocortical cells. [electronic resource]
- Molecular and cellular endocrinology Jan 2012
- 165-75 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1872-8057
10.1016/j.mce.2011.08.003 doi
Adrenal Cortex--cytology Bucladesine--pharmacology Calcium Signaling Calcium-Calmodulin-Dependent Protein Kinase Type 2--metabolism Cell Line Cholesterol--metabolism Dehydroepiandrosterone--metabolism Enzyme Activation Gene Expression Regulation Humans Hydrocortisone--biosynthesis Lysophospholipids--pharmacology MAP Kinase Signaling System Pertussis Toxin--pharmacology Phosphoproteins--genetics Phosphorylation Receptors, GABA--genetics Receptors, LDL--genetics Scavenger Receptors, Class B--genetics Sphingosine--analogs & derivatives Sterol Esterase--genetics Type C Phospholipases--metabolism Steroidogenic Acute Regulatory Protein