TY - GEN AU - Domínguez-Kelly,Raquel AU - Martín,Yusé AU - Koundrioukoff,Stephane AU - Tanenbaum,Marvin E AU - Smits,Veronique A J AU - Medema,René H AU - Debatisse,Michelle AU - Freire,Raimundo TI - Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease SN - 1540-8140 PY - 2011///1014 KW - CDC2 Protein Kinase KW - metabolism KW - Cell Cycle Proteins KW - genetics KW - Cell Line, Tumor KW - Checkpoint Kinase 1 KW - Cyclin-Dependent Kinase 2 KW - DNA Damage KW - DNA Replication KW - drug effects KW - DNA-Binding Proteins KW - Endodeoxyribonucleases KW - Endonucleases KW - Flow Cytometry KW - Genomic Instability KW - HEK293 Cells KW - High-Throughput Screening Assays KW - Histones KW - Humans KW - Hydroxyurea KW - pharmacology KW - Microscopy, Fluorescence KW - Mutation KW - Nuclear Proteins KW - Nucleic Acid Synthesis Inhibitors KW - Phosphorylation KW - Protein Kinases KW - Protein-Tyrosine Kinases KW - RNA Interference KW - S Phase KW - Time Factors KW - Transfection N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1083/jcb.201101047 ER -