TY - GEN AU - Wu,Juan AU - Ma,Hui AU - Qu,Qing AU - Zhou,Wen-Jiang AU - Luo,Yu-Ping AU - Thangaraj,Harry AU - Lowrie,Dougtas B AU - Fan,Xiao-Yong TI - Incorporation of immunostimulatory motifs in the transcribed region of a plasmid DNA vaccine enhances Th1 immune responses and therapeutic effect against Mycobacterium tuberculosis in mice SN - 1873-2518 PY - 2012///0123 KW - Amino Acid Motifs KW - genetics KW - Animals KW - Antibodies, Bacterial KW - blood KW - B7-1 Antigen KW - biosynthesis KW - B7-2 Antigen KW - Bacterial Load KW - Bacterial Proteins KW - Cell Line KW - Chaperonin 60 KW - Cytokines KW - Gene Expression KW - Gene Expression Profiling KW - Immunoglobulin G KW - Immunologic Factors KW - Lung KW - microbiology KW - Macrophages KW - immunology KW - Mice KW - Mycobacterium leprae KW - Mycobacterium tuberculosis KW - Plasmids KW - Spleen KW - Th1 Cells KW - Tuberculosis KW - Tuberculosis Vaccines KW - administration & dosage KW - Vaccines, DNA KW - Vaccines, Synthetic N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.vaccine.2011.08.020 ER -