TY  - GEN
AU  - Zhang,Zhihui
AU  - Baubet,Valérie
AU  - Ventocilla,Christian
AU  - Xiang,Chaomei
AU  - Dahmane,Nadia
AU  - Winkler,Jeffrey D
TI  - Stereoselective synthesis of F-ring saturated estrone-derived inhibitors of Hedgehog signaling based on cyclopamine
SN  - 1523-7052
PY  - 2011///1122
KW  - Animals
KW  - Cell Line
KW  - Cell Survival
KW  - drug effects
KW  - Crystallography, X-Ray
KW  - Cyclization
KW  - Estrone
KW  - analogs & derivatives
KW  - Hedgehog Proteins
KW  - antagonists & inhibitors
KW  - Humans
KW  - Models, Molecular
KW  - Molecular Conformation
KW  - Signal Transduction
KW  - Stereoisomerism
KW  - Structure-Activity Relationship
KW  - Veratrum Alkaloids
KW  - chemistry
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1021/ol2017966
ER  -