Zhang, Zhihui <br/><br/>
Stereoselective synthesis of F-ring saturated estrone-derived inhibitors of Hedgehog signaling based on cyclopamine.  [electronic resource] 

 -  Organic letters  Sep 2011 
 - 4786-9 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1523-7052 
<br/><br/><label>Standard No.: </label>10.1021/ol2017966  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cell Line<br/>Cell Survival--drug effects<br/>Crystallography, X-Ray<br/>Cyclization<br/>Estrone--analogs & derivatives<br/>Hedgehog Proteins--antagonists & inhibitors<br/>Humans<br/>Models, Molecular<br/>Molecular Conformation<br/>Signal Transduction--drug effects<br/>Stereoisomerism<br/>Structure-Activity Relationship<br/>Veratrum Alkaloids--chemistry