Chen, Yuan <br/><br/>
Determination of time-dependent inactivation of CYP3A4 in cryopreserved human hepatocytes and assessment of human drug-drug interactions.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  Nov 2011 
 - 2085-92 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1521-009X 
<br/><br/><label>Standard No.: </label>10.1124/dmd.111.040634  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Cryopreservation<br/>Cytochrome P-450 CYP3A--metabolism<br/>Cytochrome P-450 CYP3A Inhibitors<br/>Diltiazem--pharmacology<br/>Drug Interactions<br/>Enzyme Activation--drug effects<br/>Enzyme Inhibitors--pharmacology<br/>Erythromycin--pharmacology<br/>Hepatocytes--drug effects<br/>Humans<br/>Microsomes, Liver--drug effects<br/>Pharmacokinetics<br/>Risk Assessment--methods<br/>Time Factors<br/>Troleandomycin--pharmacology<br/>Verapamil--pharmacology