Doshi, Utkarsh
Luciferin IPA-based higher throughput human hepatocyte screening assays for CYP3A4 inhibition and induction. [electronic resource]
- Journal of biomolecular screening Sep 2011
- 903-9 p. digital
Publication Type: Journal Article
ISSN: 1552-454X
Standard No.: 10.1177/1087057111414900 doi
Subjects--Topical Terms: Automation, Laboratory Biological Products--analysis Cell Survival--drug effects Cells, Cultured Cryopreservation Cytochrome P-450 CYP3A--metabolism Cytochrome P-450 CYP3A Inhibitors Drug Evaluation, Preclinical--methods Drug Interactions Enzyme Induction Enzyme Inhibitors--pharmacology Firefly Luciferin--analogs & derivatives Hepatocytes--cytology High-Throughput Screening Assays Humans Inhibitory Concentration 50 Kinetics Reproducibility of Results Sensitivity and Specificity