TY - GEN AU - Thorp,Edward AU - Vaisar,Tomas AU - Subramanian,Manikandan AU - Mautner,Lauren AU - Blobel,Carl AU - Tabas,Ira TI - Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK) SN - 1083-351X PY - 2011///1123 KW - ADAM Proteins KW - chemistry KW - ADAM17 Protein KW - Adaptor Proteins, Vesicular Transport KW - metabolism KW - Amino Acid Sequence KW - Animals KW - Lipopolysaccharides KW - pharmacology KW - Mass Spectrometry KW - Mice KW - Mice, Inbred C57BL KW - Molecular Sequence Data KW - Myeloid Differentiation Factor 88 KW - NADP KW - deficiency KW - Proline KW - Protein Kinase C-delta KW - Protein Processing, Post-Translational KW - drug effects KW - Proto-Oncogene Proteins KW - Reactive Oxygen Species KW - Receptor Protein-Tyrosine Kinases KW - Sequence Deletion KW - Signal Transduction KW - Solubility KW - Toll-Like Receptor 4 KW - c-Mer Tyrosine Kinase KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1074/jbc.M111.263020 ER -