TY - GEN AU - Narita,Minoru AU - Imai,Satoshi AU - Nakamura,Atsushi AU - Ozeki,Ayumi AU - Asato,Megumi AU - Rahmadi,Mahardian AU - Sudo,Yuka AU - Hojo,Minoru AU - Uezono,Yasuhito AU - Devi,Lakshmi A AU - Kuzumaki,Naoko AU - Suzuki,Tsutomu TI - Possible involvement of prolonging spinal µ-opioid receptor desensitization in the development of antihyperalgesic tolerance to µ-opioids under a neuropathic pain-like state SN - 1369-1600 PY - 2013///1029 KW - Analgesics, Opioid KW - administration & dosage KW - Animals KW - Dose-Response Relationship, Drug KW - Drug Tolerance KW - physiology KW - Female KW - Fentanyl KW - GTP-Binding Proteins KW - drug effects KW - Guanosine 5'-O-(3-Thiotriphosphate) KW - metabolism KW - Hot Temperature KW - Hyperalgesia KW - drug therapy KW - Injections, Subcutaneous KW - Ligation KW - Male KW - Mice KW - Mice, Knockout KW - Morphine KW - Neuralgia KW - Oxycodone KW - Pain Measurement KW - methods KW - Pain Threshold KW - Radioligand Assay KW - Receptors, Opioid, mu KW - agonists KW - Sciatic Nerve KW - surgery KW - Sodium Chloride KW - Spinal Cord KW - beta-Endorphin KW - genetics N1 - Publication Type: Journal Article UR - https://doi.org/10.1111/j.1369-1600.2011.00354.x ER -