Narita, Minoru <br/><br/>
Possible involvement of prolonging spinal µ-opioid receptor desensitization in the development of antihyperalgesic tolerance to µ-opioids under a neuropathic pain-like state.  [electronic resource] 

 -  Addiction biology  Jul 2013 
 - 614-22 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1369-1600 
<br/><br/><label>Standard No.: </label>10.1111/j.1369-1600.2011.00354.x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Analgesics, Opioid--administration & dosage<br/>Animals<br/>Dose-Response Relationship, Drug<br/>Drug Tolerance--physiology<br/>Female<br/>Fentanyl--administration & dosage<br/>GTP-Binding Proteins--drug effects<br/>Guanosine 5'-O-(3-Thiotriphosphate)--metabolism<br/>Hot Temperature<br/>Hyperalgesia--drug therapy<br/>Injections, Subcutaneous<br/>Ligation<br/>Male<br/>Mice<br/>Mice, Knockout<br/>Morphine--administration & dosage<br/>Neuralgia--drug therapy<br/>Oxycodone--administration & dosage<br/>Pain Measurement--methods<br/>Pain Threshold--drug effects<br/>Radioligand Assay<br/>Receptors, Opioid, mu--agonists<br/>Sciatic Nerve--surgery<br/>Sodium Chloride--administration & dosage<br/>Spinal Cord--metabolism<br/>beta-Endorphin--genetics