Reddy, M V Ramana

Discovery of a clinical stage multi-kinase inhibitor sodium (E)-2-acetate (ON 01910.Na): synthesis, structure-activity relationship, and biological activity. [electronic resource] - Journal of medicinal chemistry Sep 2011 - 6254-76 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1520-4804

10.1021/jm200570p doi


Animals
Antineoplastic Agents--chemical synthesis
Apoptosis
Biological Availability
Cell Line, Tumor
Drug Resistance, Multiple
Drug Resistance, Neoplasm
Drug Screening Assays, Antitumor
Female
Glycine--analogs & derivatives
Humans
Mice
Mice, Nude
Neoplasm Transplantation
Protein Kinase Inhibitors--chemical synthesis
Stereoisomerism
Structure-Activity Relationship
Sulfones--chemical synthesis
Transplantation, Heterologous