TY - GEN AU - Menard,Laurence AU - Saadoun,David AU - Isnardi,Isabelle AU - Ng,Yen-Shing AU - Meyers,Greta AU - Massad,Christopher AU - Price,Christina AU - Abraham,Clara AU - Motaghedi,Roja AU - Buckner,Jane H AU - Gregersen,Peter K AU - Meffre,Eric TI - The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans SN - 1558-8238 PY - 2011///1031 KW - Alleles KW - Autoantibodies KW - immunology KW - Autoimmune Diseases KW - genetics KW - Autoimmunity KW - B-Lymphocytes KW - cytology KW - Genetic Predisposition to Disease KW - Humans KW - Isoenzymes KW - Polymorphism, Single Nucleotide KW - Protein Tyrosine Phosphatase, Non-Receptor Type 22 KW - Risk Factors KW - Self Tolerance N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI45790 ER -