Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. [electronic resource]
- Science (New York, N.Y.) Aug 2011
- 1154-7 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1095-9203
10.1126/science.1206923 doi
Carcinoma--drug therapy Carcinoma, Squamous Cell Cell Cycle Proteins--genetics Codon, Nonsense Exons F-Box Proteins--genetics F-Box-WD Repeat-Containing Protein 7 Gene Dosage Genes, Tumor Suppressor Genes, p53 Head and Neck Neoplasms--drug therapy Humans INDEL Mutation Mutation Mutation, Missense Neoplasms, Squamous Cell--drug therapy Oligonucleotide Array Sequence Analysis Oncogenes Papillomaviridae--isolation & purification Papillomavirus Infections--virology Receptor, Notch1--chemistry Sequence Analysis, DNA Smoking Squamous Cell Carcinoma of Head and Neck Nicotiana Ubiquitin-Protein Ligases--genetics