TY - GEN AU - Schelter,Florian AU - Grandl,Martina AU - Seubert,Bastian AU - Schaten,Susanne AU - Hauser,Stephanie AU - Gerg,Michael AU - Boccaccio,Carla AU - Comoglio,Paolo AU - Krüger,Achim TI - Tumor cell-derived Timp-1 is necessary for maintaining metastasis-promoting Met-signaling via inhibition of Adam-10 SN - 1573-7276 PY - 2012///0110 KW - ADAM Proteins KW - antagonists & inhibitors KW - ADAM10 Protein KW - Amyloid Precursor Protein Secretases KW - Animals KW - Blotting, Western KW - Cell Proliferation KW - Cells, Cultured KW - Gene Expression Regulation, Neoplastic KW - Hepatocyte Growth Factor KW - pharmacology KW - Humans KW - Kidney KW - cytology KW - Liver Neoplasms, Experimental KW - genetics KW - Membrane Proteins KW - Mice KW - Mice, Inbred DBA KW - Phosphorylation KW - drug effects KW - Proto-Oncogene Proteins c-met KW - RNA, Messenger KW - RNA, Small Interfering KW - Real-Time Polymerase Chain Reaction KW - Reverse Transcriptase Polymerase Chain Reaction KW - Signal Transduction KW - Survival Rate KW - Tissue Inhibitor of Metalloproteinase-1 KW - Tumor Microenvironment N1 - Publication Type: Journal Article UR - https://doi.org/10.1007/s10585-011-9410-z ER -