Schelter, Florian

Tumor cell-derived Timp-1 is necessary for maintaining metastasis-promoting Met-signaling via inhibition of Adam-10. [electronic resource] - Clinical & experimental metastasis Dec 2011 - 793-802 p. digital

Publication Type: Journal Article

1573-7276

10.1007/s10585-011-9410-z doi


ADAM Proteins--antagonists & inhibitors
ADAM10 Protein
Amyloid Precursor Protein Secretases--antagonists & inhibitors
Animals
Blotting, Western
Cell Proliferation
Cells, Cultured
Gene Expression Regulation, Neoplastic
Hepatocyte Growth Factor--pharmacology
Humans
Kidney--cytology
Liver Neoplasms, Experimental--genetics
Membrane Proteins--antagonists & inhibitors
Mice
Mice, Inbred DBA
Phosphorylation--drug effects
Proto-Oncogene Proteins c-met--antagonists & inhibitors
RNA, Messenger--genetics
RNA, Small Interfering--genetics
Real-Time Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Survival Rate
Tissue Inhibitor of Metalloproteinase-1--antagonists & inhibitors
Tumor Microenvironment