Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death. [electronic resource]
- Cellular and molecular life sciences : CMLS Feb 2012
- 629-40 p. digital
Publication Type: Journal Article
1420-9071
10.1007/s00018-011-0767-6 doi
Anaphase Apoptosis Cell Line DNA End-Joining Repair DNA-Activated Protein Kinase--antagonists & inhibitors G-Quadruplexes Homologous Recombination Humans Ligands Metaphase Mitosis--genetics Nuclear Proteins--antagonists & inhibitors Pyridines--pharmacology Quinolines--pharmacology RNA Interference RNA, Small Interfering--metabolism Rad51 Recombinase--antagonists & inhibitors Telomere--metabolism