TY - GEN AU - Feldmann,Georg AU - Mishra,Anjali AU - Bisht,Savita AU - Karikari,Collins AU - Garrido-Laguna,Ignacio AU - Rasheed,Zeshaan AU - Ottenhof,Niki A AU - Dadon,Tikva AU - Alvarez,Hector AU - Fendrich,Volker AU - Rajeshkumar,N V AU - Matsui,William AU - Brossart,Peter AU - Hidalgo,Manuel AU - Bannerji,Rajat AU - Maitra,Anirban AU - Nelkin,Barry D TI - Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models SN - 1555-8576 PY - 2012///0328 KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - Bridged Bicyclo Compounds, Heterocyclic KW - administration & dosage KW - Cell Line, Tumor KW - Cell Movement KW - drug effects KW - Cell Proliferation KW - Cyclic N-Oxides KW - Cyclin-Dependent Kinases KW - antagonists & inhibitors KW - Deoxycytidine KW - Drug Resistance, Neoplasm KW - genetics KW - Enzyme Inhibitors KW - Humans KW - Indolizines KW - Male KW - Mice KW - Mice, Nude KW - Pancreatic Neoplasms KW - drug therapy KW - Phosphorylation KW - Pyridinium Compounds KW - Receptors, Notch KW - Retinoblastoma Protein KW - metabolism KW - Signal Transduction KW - Transforming Growth Factor beta KW - Xenograft Model Antitumor Assays KW - ral GTP-Binding Proteins KW - Gemcitabine N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.4161/cbt.12.7.16475 ER -