Tan, Meng-Kwang Marcus
SCF(FBXO22) regulates histone H3 lysine 9 and 36 methylation levels by targeting histone demethylase KDM4A for ubiquitin-mediated proteasomal degradation. [electronic resource]
- Molecular and cellular biology Sep 2011
- 3687-99 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1098-5549
10.1128/MCB.05746-11 doi
Basic Helix-Loop-Helix Transcription Factors--biosynthesis
Boronic Acids--pharmacology
Bortezomib
Cell Cycle
Cell Cycle Proteins
Cell Line, Tumor
Chromatin
Cyclopentanes--pharmacology
Epigenesis, Genetic
F-Box Proteins--metabolism
Gene Expression Regulation
HEK293 Cells
HeLa Cells
Histone Demethylases--metabolism
Histones--metabolism
Humans
Jumonji Domain-Containing Histone Demethylases--biosynthesis
Mass Spectrometry
Methylation
Proteasome Endopeptidase Complex--metabolism
Protein Processing, Post-Translational
Pyrazines--pharmacology
Pyrimidines--pharmacology
RNA Interference
RNA, Small Interfering
Receptors, Cytoplasmic and Nuclear--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Ubiquitination