TY - GEN AU - Mitchell,Duane A AU - Cui,Xiuyu AU - Schmittling,Robert J AU - Sanchez-Perez,Luis AU - Snyder,David J AU - Congdon,Kendra L AU - Archer,Gary E AU - Desjardins,Annick AU - Friedman,Allan H AU - Friedman,Henry S AU - Herndon,James E AU - McLendon,Roger E AU - Reardon,David A AU - Vredenburgh,James J AU - Bigner,Darell D AU - Sampson,John H TI - Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans SN - 1528-0020 PY - 2011///1121 KW - Adult KW - Animals KW - Antibodies, Monoclonal KW - pharmacology KW - Antibodies, Monoclonal, Humanized KW - Antineoplastic Agents, Alkylating KW - therapeutic use KW - Brain Neoplasms KW - immunology KW - Cancer Vaccines KW - Cells, Cultured KW - Combined Modality Therapy KW - Dacarbazine KW - analogs & derivatives KW - Daclizumab KW - Drug Evaluation, Preclinical KW - Glioblastoma KW - Humans KW - Immunoglobulin G KW - Immunotherapy KW - methods KW - Interleukin-2 Receptor alpha Subunit KW - antagonists & inhibitors KW - Lymphocyte Depletion KW - Lymphopenia KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Middle Aged KW - Substrate Specificity KW - drug effects KW - T-Lymphocytes, Regulatory KW - cytology KW - Temozolomide KW - Young Adult N1 - Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1182/blood-2011-02-334565 ER -