TY - GEN AU - Ashoorzadeh,Amir AU - Atwell,Graham J AU - Pruijn,Frederik B AU - Wilson,William R AU - Tercel,Moana AU - Denny,William A AU - Stevenson,Ralph J TI - The effect of sulfonate leaving groups on the hypoxia-selective toxicity of nitro analogs of the duocarmycins SN - 1464-3391 PY - 2012///0208 KW - Alkanesulfonates KW - chemical synthesis KW - Antineoplastic Agents, Alkylating KW - Cell Hypoxia KW - drug effects KW - DNA KW - chemistry KW - Drug Design KW - Drug Screening Assays, Antitumor KW - Duocarmycins KW - Female KW - Humans KW - Indoles KW - Nitro Compounds KW - Prodrugs KW - Pyrrolidinones KW - Structure-Activity Relationship KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bmc.2011.06.073 ER -