dos Santos, Jean Leandro

Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms. [electronic resource] - Journal of medicinal chemistry Aug 2011 - 5811-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/jm200531f doi


Acetic Acid
Analgesics--chemical synthesis
Anemia, Sickle Cell--drug therapy
Animals
Anti-Inflammatory Agents--chemical synthesis
Antisickling Agents--chemical synthesis
Capsaicin
Colic--chemically induced
Drug Design
Ear--pathology
Edema--chemically induced
Female
Male
Mice
Mice, Transgenic
Models, Chemical
Molecular Structure
Peritonitis--chemically induced
Thalidomide--chemical synthesis
Thioglycolates
Tumor Necrosis Factor-alpha--metabolism