TY  - GEN
AU  - Xie,Jianling
AU  - Ponuwei,Godwin A
AU  - Moore,Claire E
AU  - Willars,Gary B
AU  - Tee,Andrew R
AU  - Herbert,Terence P
TI  - cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity
SN  - 1873-3913
PY  - 2012///0113
KW  - 1-Methyl-3-isobutylxanthine
KW  - pharmacology
KW  - Adaptor Proteins, Signal Transducing
KW  - Adenylate Kinase
KW  - metabolism
KW  - Amino Acids
KW  - Animals
KW  - Carrier Proteins
KW  - Cell Cycle Proteins
KW  - Cell Line
KW  - Colforsin
KW  - Cyclic AMP
KW  - chemistry
KW  - Eukaryotic Initiation Factors
KW  - Gene Deletion
KW  - Gene Knockout Techniques
KW  - Humans
KW  - Insulin
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Mice
KW  - Monomeric GTP-Binding Proteins
KW  - genetics
KW  - Multiprotein Complexes
KW  - Neuropeptides
KW  - Phosphodiesterase Inhibitors
KW  - Phosphoproteins
KW  - Phosphorylation
KW  - Protein Binding
KW  - Protein Kinases
KW  - Proteins
KW  - agonists
KW  - Ras Homolog Enriched in Brain Protein
KW  - Recombinant Proteins
KW  - Ribosomal Protein S6 Kinases, 90-kDa
KW  - Signal Transduction
KW  - TOR Serine-Threonine Kinases
KW  - Transcription Factors
KW  - Tuberous Sclerosis Complex 2 Protein
KW  - Tumor Suppressor Proteins
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.cellsig.2011.06.025
ER  -