TY - GEN AU - Ho,Sheng-Yow AU - Wu,Wei-Jr AU - Chiu,Hui-Wen AU - Chen,Yi-An AU - Ho,Yuan-Soon AU - Guo,How-Ran AU - Wang,Ying-Jan TI - Arsenic trioxide and radiation enhance apoptotic effects in HL-60 cells through increased ROS generation and regulation of JNK and p38 MAPK signaling pathways SN - 1872-7786 PY - 2011///1003 KW - Acetylcysteine KW - pharmacology KW - Antineoplastic Agents KW - Apoptosis KW - drug effects KW - Arsenic Trioxide KW - Arsenicals KW - Caspase 3 KW - metabolism KW - Cell Cycle KW - Cell Cycle Proteins KW - Cell Survival KW - Cyclins KW - DNA Fragmentation KW - Dose-Response Relationship, Drug KW - Dose-Response Relationship, Radiation KW - F-Box Proteins KW - F-Box-WD Repeat-Containing Protein 7 KW - HL-60 Cells KW - Humans KW - JNK Mitogen-Activated Protein Kinases KW - antagonists & inhibitors KW - Membrane Potential, Mitochondrial KW - Models, Biological KW - Oxides KW - Phosphorylation KW - Poly(ADP-ribose) Polymerases KW - Proto-Oncogene Proteins c-bcl-2 KW - Reactive Oxygen Species KW - Signal Transduction KW - Tumor Stem Cell Assay KW - Ubiquitin-Protein Ligases KW - X-Rays KW - bcl-2-Associated X Protein KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cbi.2011.06.007 ER -