Ho, Sheng-Yow <br/><br/>
Arsenic trioxide and radiation enhance apoptotic effects in HL-60 cells through increased ROS generation and regulation of JNK and p38 MAPK signaling pathways.  [electronic resource] 

 -  Chemico-biological interactions  Sep 2011 
 - 162-71 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1872-7786 
<br/><br/><label>Standard No.: </label>10.1016/j.cbi.2011.06.007  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylcysteine--pharmacology<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis--drug effects<br/>Arsenic Trioxide<br/>Arsenicals--pharmacology<br/>Caspase 3--metabolism<br/>Cell Cycle--drug effects<br/>Cell Cycle Proteins--metabolism<br/>Cell Survival--drug effects<br/>Cyclins--metabolism<br/>DNA Fragmentation--drug effects<br/>Dose-Response Relationship, Drug<br/>Dose-Response Relationship, Radiation<br/>F-Box Proteins--metabolism<br/>F-Box-WD Repeat-Containing Protein 7<br/>HL-60 Cells<br/>Humans<br/>JNK Mitogen-Activated Protein Kinases--antagonists & inhibitors<br/>Membrane Potential, Mitochondrial--drug effects<br/>Models, Biological<br/>Oxides--pharmacology<br/>Phosphorylation--drug effects<br/>Poly(ADP-ribose) Polymerases--metabolism<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>Reactive Oxygen Species--metabolism<br/>Signal Transduction--drug effects<br/>Tumor Stem Cell Assay<br/>Ubiquitin-Protein Ligases--metabolism<br/>X-Rays<br/>bcl-2-Associated X Protein--metabolism<br/>p38 Mitogen-Activated Protein Kinases--antagonists & inhibitors