TY - GEN AU - Azuma,Junichi AU - Hasunuma,Tomoko AU - Kubo,Masanori AU - Miyatake,Masaya AU - Koue,Toshiko AU - Higashi,Koushi AU - Fujiwara,Tsutomu AU - Kitahara,Sachiko AU - Katano,Tamiki AU - Hara,Sumiko TI - The relationship between clinical pharmacokinetics of aripiprazole and CYP2D6 genetic polymorphism: effects of CYP enzyme inhibition by coadministration of paroxetine or fluvoxamine SN - 1432-1041 PY - 2012///0504 KW - Adult KW - Antipsychotic Agents KW - adverse effects KW - Aripiprazole KW - Biotransformation KW - Cytochrome P-450 CYP2D6 KW - genetics KW - Cytochrome P-450 CYP2D6 Inhibitors KW - Cytochrome P-450 CYP3A KW - Cytochrome P-450 CYP3A Inhibitors KW - Drug Interactions KW - Enzyme Inhibitors KW - Fluvoxamine KW - Genetic Association Studies KW - Half-Life KW - Humans KW - Japan KW - Male KW - Metabolic Clearance Rate KW - drug effects KW - Paroxetine KW - Piperazines KW - Polymorphism, Genetic KW - Quinolones KW - Serotonin 5-HT2 Receptor Antagonists KW - Selective Serotonin Reuptake Inhibitors KW - Young Adult N1 - Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s00228-011-1094-4 ER -