Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm. [electronic resource]
- Circulation research Aug 2011
- 360-4 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1524-4571
10.1161/CIRCRESAHA.111.249540 doi
Cardiac Myosins--genetics Cell Differentiation--drug effects Cell Line Dose-Response Relationship, Drug Drug Discovery Embryonic Stem Cells--drug effects Gene Expression Profiling Gene Expression Regulation, Developmental--drug effects Genes, Reporter High-Throughput Screening Assays Humans Luminescent Proteins--biosynthesis Mesoderm--cytology Microscopy, Fluorescence Myocytes, Cardiac--drug effects Myosin Heavy Chains--genetics Promoter Regions, Genetic--drug effects Signal Transduction--drug effects Small Molecule Libraries Time Factors Transfection Wnt Proteins--antagonists & inhibitors Red Fluorescent Protein