TY  - GEN
AU  - Chmielecki,Juliann
AU  - Foo,Jasmine
AU  - Oxnard,Geoffrey R
AU  - Hutchinson,Katherine
AU  - Ohashi,Kadoaki
AU  - Somwar,Romel
AU  - Wang,Lu
AU  - Amato,Katherine R
AU  - Arcila,Maria
AU  - Sos,Martin L
AU  - Socci,Nicholas D
AU  - Viale,Agnes
AU  - de Stanchina,Elisa
AU  - Ginsberg,Michelle S
AU  - Thomas,Roman K
AU  - Kris,Mark G
AU  - Inoue,Akira
AU  - Ladanyi,Marc
AU  - Miller,Vincent A
AU  - Michor,Franziska
AU  - Pao,William
TI  - Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling
SN  - 1946-6242
PY  - 2011///1115
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Carcinoma, Non-Small-Cell Lung
KW  - drug therapy
KW  - Cell Line, Tumor
KW  - Drug Resistance, Neoplasm
KW  - genetics
KW  - ErbB Receptors
KW  - Erlotinib Hydrochloride
KW  - Evolution, Molecular
KW  - Female
KW  - Gefitinib
KW  - Genes, erbB-1
KW  - drug effects
KW  - Humans
KW  - Mice
KW  - Mice, Nude
KW  - Models, Theoretical
KW  - Mutation
KW  - Neoplasm Transplantation
KW  - Protein Kinase Inhibitors
KW  - Quinazolines
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1126/scitranslmed.3002356
ER  -