Nunes, Gabriel L C <br/><br/>
Mechanism of heparin acceleration of tissue inhibitor of metalloproteases-1 (TIMP-1) degradation by the human neutrophil elastase.  [electronic resource] 

 -  PloS one  2011 
 - e21525 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0021525  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Catalytic Domain<br/>Fluorescence Resonance Energy Transfer<br/>Fluorescent Dyes--metabolism<br/>Heparin--pharmacology<br/>Humans<br/>Hydrogen-Ion Concentration--drug effects<br/>Hydrolysis--drug effects<br/>Kinetics<br/>Leukocyte Elastase--metabolism<br/>Models, Molecular<br/>Peptides--metabolism<br/>Protein Processing, Post-Translational--drug effects<br/>Substrate Specificity--drug effects<br/>Tissue Inhibitor of Metalloproteinase-1--metabolism<br/>Up-Regulation--drug effects