TY  - GEN
AU  - Kaspera,Rüdiger
AU  - Naraharisetti,Suresh B
AU  - Evangelista,Eric A
AU  - Marciante,Kristin D
AU  - Psaty,Bruce M
AU  - Totah,Rheem A
TI  - Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5
SN  - 1873-2968
PY  - 2011///1003
KW  - Amino Acid Sequence
KW  - Animals
KW  - Aryl Hydrocarbon Hydroxylases
KW  - genetics
KW  - Catalysis
KW  - Cytochrome P-450 CYP2C8
KW  - Cytochromes b5
KW  - Escherichia coli
KW  - enzymology
KW  - Humans
KW  - In Vitro Techniques
KW  - Inactivation, Metabolic
KW  - Kinetics
KW  - Microsomes, Liver
KW  - drug effects
KW  - Models, Molecular
KW  - Molecular Sequence Data
KW  - NADPH-Ferrihemoprotein Reductase
KW  - Oxidation-Reduction
KW  - Pharmaceutical Preparations
KW  - metabolism
KW  - Polymorphism, Genetic
KW  - Protein Binding
KW  - Rats
KW  - Recombinant Proteins
KW  - Sequence Alignment
KW  - Substrate Specificity
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1016/j.bcp.2011.06.027
ER  -