Fusion tyrosine kinase NPM-ALK Deregulates MSH2 and suppresses DNA mismatch repair function novel insights into a potent oncoprotein. [electronic resource]
- The American journal of pathology Jul 2011
- 411-21 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1525-2191
10.1016/j.ajpath.2011.03.045 doi
Cytoplasm--metabolism DNA Damage DNA Mismatch Repair DNA-Binding Proteins--genetics Humans Immunoenzyme Techniques Immunoprecipitation Lymphoma, Large B-Cell, Diffuse--genetics Lymphoma, Large-Cell, Anaplastic--genetics Microsatellite Instability MutS Homolog 2 Protein--genetics Phosphorylation Protein Multimerization Protein Transport Protein-Tyrosine Kinases--genetics Tumor Cells, Cultured Tyrosine--metabolism