TY - GEN AU - Stepan,Antonia F AU - Walker,Daniel P AU - Bauman,Jonathan AU - Price,David A AU - Baillie,Thomas A AU - Kalgutkar,Amit S AU - Aleo,Michael D TI - Structural alert/reactive metabolite concept as applied in medicinal chemistry to mitigate the risk of idiosyncratic drug toxicity: a perspective based on the critical examination of trends in the top 200 drugs marketed in the United States SN - 1520-5010 PY - 2012///0118 KW - Animals KW - Drug Discovery KW - methods KW - Drug Recalls KW - Drug-Related Side Effects and Adverse Reactions KW - epidemiology KW - Humans KW - Pharmaceutical Preparations KW - chemistry KW - United States N1 - Publication Type: Journal Article; Review UR - https://doi.org/10.1021/tx200168d ER -