Ling, Yi-He <br/><br/>
PM02734 (elisidepsin) induces caspase-independent cell death associated with features of autophagy, inhibition of the Akt/mTOR signaling pathway, and activation of death-associated protein kinase.  [electronic resource] 

 -  Clinical cancer research : an official journal of the American Association for Cancer Research  Aug 2011 
 - 5353-66 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Retracted Publication 
<br/><br/><label>ISSN: </label>1557-3265 
<br/><br/><label>Standard No.: </label>10.1158/1078-0432.CCR-10-1948  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenine--analogs & derivatives<br/>Animals<br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins--genetics<br/>Autophagy--drug effects<br/>Autophagy-Related Protein 5<br/>Calcium-Calmodulin-Dependent Protein Kinases--genetics<br/>Carcinoma, Non-Small-Cell Lung--drug therapy<br/>Caspases--metabolism<br/>Cell Line, Tumor<br/>Death-Associated Protein Kinases<br/>Depsipeptides--pharmacology<br/>Enzyme Activation--drug effects<br/>Green Fluorescent Proteins--genetics<br/>Humans<br/>Immunoblotting<br/>Lung Neoplasms--drug therapy<br/>Mice<br/>Mice, Nude<br/>Microscopy, Fluorescence<br/>Microtubule-Associated Proteins--genetics<br/>Phosphorylation--drug effects<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>RNA Interference<br/>Signal Transduction--drug effects<br/>TOR Serine-Threonine Kinases--metabolism<br/>Xenograft Model Antitumor Assays