The use of molecular markers as a method to predict the response to neoadjuvant therapy for advanced stage rectal adenocarcinoma. [electronic resource]
- Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland May 2012
- 555-61 p. digital
Publication Type: Journal Article
1463-1318
10.1111/j.1463-1318.2011.02697.x doi
Adenocarcinoma--metabolism Adult Aged Aged, 80 and over Antimetabolites, Antineoplastic--therapeutic use Apoptotic Protease-Activating Factor 1--metabolism Biomarkers, Tumor--metabolism Chemoradiotherapy Chi-Square Distribution Cyclin-Dependent Kinase Inhibitor p21--metabolism Cyclin-Dependent Kinase Inhibitor p27--metabolism Cyclooxygenase 2--metabolism Dose Fractionation, Radiation Female Fluorouracil--therapeutic use Humans Male Middle Aged Multivariate Analysis Neoadjuvant Therapy Neoplasm Staging Proto-Oncogene Proteins c-bcl-2--metabolism Rectal Neoplasms--metabolism Statistics, Nonparametric Tumor Suppressor Protein p53--metabolism Vascular Endothelial Growth Factor A--metabolism bcl-2-Associated X Protein--metabolism