TY - GEN AU - Hanai,Jun-ichi AU - Doro,Nathaniel AU - Sasaki,Atsuo T AU - Kobayashi,Susumu AU - Cantley,Lewis C AU - Seth,Pankaj AU - Sukhatme,Vikas P TI - Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways SN - 1097-4652 PY - 2012///0305 KW - ATP Citrate (pro-S)-Lyase KW - antagonists & inhibitors KW - Animals KW - Apoptosis KW - Cell Cycle KW - Cell Line, Tumor KW - Cell Proliferation KW - Combined Modality Therapy KW - Epithelial-Mesenchymal Transition KW - ErbB Receptors KW - genetics KW - Female KW - Gene Knockdown Techniques KW - Humans KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors KW - therapeutic use KW - Lung Neoplasms KW - drug therapy KW - MAP Kinase Signaling System KW - drug effects KW - Mice KW - Mutation KW - Phosphoinositide-3 Kinase Inhibitors KW - Proto-Oncogene Proteins c-akt KW - Signal Transduction KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/jcp.22895 ER -