TY  - GEN
AU  - Russell,Ryan C
AU  - Sufan,Roxana I
AU  - Zhou,Bing
AU  - Heir,Pardeep
AU  - Bunda,Severa
AU  - Sybingco,Stephanie S
AU  - Greer,Samantha N
AU  - Roche,Olga
AU  - Heathcote,Samuel A
AU  - Chow,Vinca W K
AU  - Boba,Lukasz M
AU  - Richmond,Terri D
AU  - Hickey,Michele M
AU  - Barber,Dwayne L
AU  - Cheresh,David A
AU  - Simon,M Celeste
AU  - Irwin,Meredith S
AU  - Kim,William Y
AU  - Ohh,Michael
TI  - Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia
SN  - 1546-170X
PY  - 2011///0920
KW  - Animals
KW  - Disease Models, Animal
KW  - Humans
KW  - Janus Kinase 2
KW  - antagonists & inhibitors
KW  - Mice
KW  - Mutation
KW  - genetics
KW  - Polycythemia
KW  - etiology
KW  - Protein Multimerization
KW  - Pyrimidines
KW  - pharmacology
KW  - Sulfonamides
KW  - Suppressor of Cytokine Signaling 1 Protein
KW  - Suppressor of Cytokine Signaling Proteins
KW  - Ubiquitin-Protein Ligases
KW  - Von Hippel-Lindau Tumor Suppressor Protein
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1038/nm.2370
ER  -