Russell, Ryan C <br/><br/>
Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.  [electronic resource] 

 -  Nature medicine  Jun 2011 
 - 845-53 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1546-170X 
<br/><br/><label>Standard No.: </label>10.1038/nm.2370  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Disease Models, Animal<br/>Humans<br/>Janus Kinase 2--antagonists & inhibitors<br/>Mice<br/>Mutation--genetics<br/>Polycythemia--etiology<br/>Protein Multimerization--genetics<br/>Pyrimidines--pharmacology<br/>Sulfonamides--pharmacology<br/>Suppressor of Cytokine Signaling 1 Protein<br/>Suppressor of Cytokine Signaling Proteins--genetics<br/>Ubiquitin-Protein Ligases--genetics<br/>Von Hippel-Lindau Tumor Suppressor Protein--genetics